ITALY, Bologna Oxidative Stress and Erythrocyte Membrane Alterations in Autism Spectrum Disorder: on Search of a Biomarker and of New Therapeutic Prospects The project is aimed at understanding why red blood cell membranes of autistic children are endowed of a number of anomalous features, as described...
ITALY, Rome, Milan Autophagy as Therapeutic Target in Relapsed/refractory Human Lymphomas The project assesses the effects of new therapeutic strategies in the light of the cellular mechanisms involved. It also aims at providing novel...
ITALY, Rome Personalized Therapy of AMD (Age Related Macular Degeneration) Patients: the Clinical Use of Personal Genome Age-related macular degeneration (AMD) is the most common irreversible cause of severe vision loss throughout the world in people aged 50 years or...
ITALY, Rome Surgical Research Study on the Effects of Minimally Invasive Surgery Versus Open Surgery in Neonates, Infants and Children Since 2009, the UOC Chirurgia Pediatrica (Pediatric Surgery Unit) has started to adopt minimally invasive techniques for various surgical diseases...
ITALY, Modena Research Study on Anticancer Drugs Targeting the Cdk2 and Efgr ProteinsThe goal of this project, which received a grant from the Nando Peretti Foundation, is to design and develop anticancer drugs targeting two important...
ITALY Investigating the Dna Replication Stress Response and its Potential for Diagnosis and Target Therapy of Cancer This project by Istituto Superiore di Sanità aims at determining molecular changes in both genomic integrity and activation of specific DNA...
ITALY, Rome Nature-Inspired Nanoprobes for the Point-Of-Care Detection of Clinically Relevant Biomarkers for Early Tumor Diagnosis The Department of Chemistry of the University of Rome, Tor Vergata has a strong track record of both teaching and research and in a recent...
ITALY, Rome Transcriptional and Micro-RNA Signature Profiling of Human Amyotrophic Lateral Sclerosis Muscles: a tool to identify pathogenic molecular networks and diagnostic biomarkers Amyotrophic lateral sclerosis is a neurodegenerative disease characterised by progressive muscular paralysis reflecting degeneration of motor...
ITALY, Rome Molecular Monitoring of Minimal Residual Disease in Chronic Myeloid Leukemia The success of tyrosine kinase inhibition of the BCR-ABL fusion gene with imatinib in the treatment of chronic myeloid leukemia (CML) has resulted...
ITALY, Lazio, Emilia Romagna, Campania, Puglia Breast Cancer early Detection Program for Underserved Women or Women at Higher Risk for Breast Cancer Breast cancer is the leading cause of deaths among women ages 40 - 59. Every year, over 37.000 women, in Italy, develop breast cancer, one every 15...
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